Fast microglial activation after severe traumatic brain injuries

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Microglial Activation in Traumatic Brain Injury

Microglia have a variety of functions in the brain, including synaptic pruning, CNS repair and mediating the immune response against peripheral infection. Microglia rapidly become activated in response to CNS damage. Depending on the nature of the stimulus, microglia can take a number of activation states, which correspond to altered microglia morphology, gene expression and function. It has be...

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ژورنال

عنوان ژورنال: International Journal of Legal Medicine

سال: 2020

ISSN: 0937-9827,1437-1596

DOI: 10.1007/s00414-020-02308-x